2. Signaling Pathways
  3. Epigenetics
  4. TET Protein

TET Protein

TET enzyme; Ten-eleven-translocation (TET) protein; Ten-eleven translocation (TET) methylcytosine dioxygenase

TET proteins, including TET1, TET2, and TET3, are a family of dioxygenases that catalyze the demethylation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC), facilitating DNA demethylation. These enzymes share a common core catalytic domain at their C termini. TET3 is highly expressed in oocytes and fertilized zygotes but decreases during cleavage, while TET1 and TET2 expression increases during pre-implantation development. TET1 is crucial for development and intestinal stem cell function. TET2 mutations are frequently found in hematologic malignancies, such as myelodysplastic syndrome and acute myeloid leukemia. TET3 plays a significant role in demethylation processes, including zygote formation, embryogenesis, axon regeneration, and synaptic transmission[1][2].

TET Protein Isoform Specific Products:

TET Protein Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-111558
    Bobcat339
    		Inhibitor 99.44%
    Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Bobcat339
  • HY-111558A
    Bobcat339 hydrochloride
    		Inhibitor 99.59%
    Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Bobcat339 hydrochloride
  • HY-12303
    OAC1
    		Activator 99.56%
    Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    OAC1
  • HY-122258
    NSC-370284
    		Inhibitor
    Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    NSC-370284
  • HY-402410
    TETi76
    		Inhibitor
    Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    TETi76
  • HY-120395
    UC-514321
    		Inhibitor ≥98.0%
    Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    UC-514321
  • HY-160638
    NSC-311068
    		Inhibitor ≥98.0%
    Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    NSC-311068
  • HY-W396714
    Succinic acid sodium
    		Inhibitor
    Ethopabate (Standard) is the analytical standard of Ethopabate. This product is intended for research and analytical applications. Ethopabate (Ethyl pabate) is an orally active antiparasitic agent. Ethopabate is often used in combination with Amprolium hydrochloride (HY-B0937A) and others to prevent and treat poultry coccidiosis, leucosis, and other diseases.
    Succinic acid sodium
TET Protein Isoform Comparison

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